Archive for the 'Diabetes & Diabetic Foot Care' Category

Skin Temps Predictive of Foot Ulcer in Diabetics

A new study published in the Journal of Foot and Ankle Research reviewed the literature back to 1960 to evaluate whether measuring skin temperatures in the diabetic foot were predictive of foot ulceration. Results support the theory that increases skin temperature in the diabetic is predictive of foot ulceration when compared with the same site [...]

Plant Chemical Berberine Lowers Blood Sugar

Berberine is a plant alkaloid found in plants such as Berberis, Coptis chinensis and goldenseal. Berberine has been used as a traditional dietary supplement because of it’s anti-fungal, anti-bacterial and anti-inflammatory effects. Berberine promotes glucose uptake in pancreatic cells and also inhibits glucosidase activity, improving glucose metabolism. In a study from the Shanghai Jiao Tong [...]

Diabetic Neuropathy Linked to Periodontal Disease

Diabetic neuropathy is nerve damage caused by diabetes and results in the loss of sensation in the toes and feet. Diabetics with neuropathy are at risk of developing an ulceration, a slow healing sore on the bottom of the foot which can lead to infection and/or amputation of part or all of the foot. Diabetic [...]

Type 2 Diabetes

According to the CDC, close to 24 million Americans have diabetes. Forty percent of those with diabetes are age 65 and older. Most of the diabetics over the age of 60 have type 2 diabetes. Social Bookmarking OptionsBlinklistBloglinesBlogmarksDiggdel.icio.usFacebookFurlMa.gnoliaNewsVineRedditStumbleUponTechnorati

Diabetic Neuropathy

Over 21 million Americans have diabetes and about 30% of diabetics over the age of 40 years have diabetic peripheral neuropathy (CDC 2005). Neuropathy is a nervous system abnormality. Peripheral refers to the nerves outside the central nervous system (brain and spinal cord). Peripheral neuropathy generally refers to sensory abnormalities in the feet, legs, hands [...]

Fruit Juice May Speed Healing of Diabetic Wounds

Diabetics are prone to developing wounds, called, ulcers, and have difficulty healing them due to multiple factors, which include poor blood flow, increased sugar levels, decreased collagen production and decreased levels of growth hormones. The Polynesian medicinal plant, Morinda Citrifolia, has been used for burns, arthritis, diabetes, circulatory conditions and wound healing. Some studies have [...]

Diabetic Amputations Can Be Prevented

Twenty-four million Americans have diabetes and 600,000 will develop foot ulcers every year. More than 25% of diabetics with ulcerations will end up with a lower extremity amputation. More than 80,00 lower extremity amputations are performed on diabetics every year. Experts say that many of these amputations are preventable with the proper education and appropriate [...]

IgM Helps Predict Diabetic Complications

A new study in BMC Medicine found that diabetics with a higher excretion of IgM (short for immunoglobulin M, an antibody present on B cells) have a three time higher risk of end stage renal disease and death from cardiovascular disease. Testing for urine IgM may help predict future diabetic complications. BMC Medicine 2009, 7:39doi:10.1186/1741-7015-7-39 [...]

Nicotine May Promote Insulin Resistance

Smokers are at a higher risk of developing diabetes and a new study could explain why smokers have an increased risk. Researchers at the Charles Drew University of Medicine and Science in Los Angeles found that the nicotine in cigarette smoke may promote insulin resistance, which causes higher blood sugar levels and leads to prediabetes. [...]

Type 1 Diabetes On The Rise in Children

The incidence of type 1 diabetes is increasing in children under 15 years of age. A new study in The Lancet reviewed European registries in 17 countries and noted 29, 311 new cases of type 1 diabetes between 1989-2003 in children before their 15th birthday. Based on the data, the authors calculated age-specific log linear [...]

Fenofibrate Reduces Diabetic Amputation Risk

Results from the Fenofibrate Intervention and Event Lowering in Diabetes (FIELD) study were reported in this month’s Diabetes Special Issue of The Lancet. University of Sydney researchers evaluated the risk of cardiovascular death and amputation in type 2 diabetics using the medication fenofibrate. Over a five year period, 9,795 diabetics ages 50 to 75 were [...]

High Triglycerides Are Associated with Nerve Loss in Diabetics

In a new study published in the journal Diabetes, elevated triglycerides were associated with the progression of diabetic neuropathy (1). Diabetic peripheral neuropathy is an abnormality of the nervous system which occurs as a result of diabetes and causes a loss of sensation in the feet and the legs. Although there are many theories for [...]

IDF Calls For International Awareness of Diabetes

The International Diabetes Federation (IDF) is calling on governments, the United Nations and the World Health Organization to recognize the impact of diabetes on global health and take immediate action to ameliorate the threat. IDF president, Professor Silink, urged these institutions to include diabetes and other non-communicable diseases, such as cardiovascular diseases (CVD) and cancer [...]

Some Diabetics at Greater Risk of Swine Flu

The CDC report released by the New England Journal of Medicine provided information on hospitalized patients with the H1N1 Flu. Those individuals who have been hospitalized or have died from the flu have been very young, elderly or had chronic medical conditions. The CDC telebriefing yesterday on human cases of H1N1 Flu stated that there [...]

Gene Therapy Hopeful Treatment for Neuropathy

Researchers in the Neurology Department at Brigham and Women’s Hospital in Boston found that injections of a growth factor gene may help improve diabetic peripheral neuropathy. The researchers randomly divided 50 patients with diabetic polyneuropathy into two groups to receive intramuscular injections of plasmid VEGF (vascular endothelial growth factor) gene or a placebo. Study participants [...]

Stem Cells Help Heal Diabetic Ulcers

Researchers at the Bristol Heart Institute found specific stem cells which helped heal chronic, ischemic diabetic ulcers. The CD133+ stem cells, along with collagen, were transplanted onto an ischemic diabetic wound. Through an indirect mechanism, the CD133+ cells promoted new blood vessel formation and accelerated healing. Social Bookmarking OptionsBlinklistBloglinesBlogmarksDiggdel.icio.usFacebookFurlMa.gnoliaNewsVineRedditStumbleUponTechnorati

Diabetics Risk Amputation in Tough Economy

Tough economic times are forcing people to make difficult decisions regarding their health care. An Associated Press analysis found that diabetics are skipping doctor visits, skimping on insulin and not purchasing other necessary diabetes medications and blood-sugar testing kits. Diabetics who do not properly control their blood sugar levels risk losing their vision, their legs [...]

FDA Approves New Diabetes Drug for Clinical Development

The FDA approved MLR-1023, a new drug for diabetes, for clinical development on March 18th, 2009. MLR-1023 was originally developed by Melior Discovery using their unique discovery platform called theraTRACE ®. theraTRACE ® was designed to uncover new indications for existing pharmaceutical compounds. Pre-clinical studies have suggested that MLR-1023 has the potential to be an [...]

Diabetics Have Higher Amputation Risk

In last month’s issue of Diabetes Care, a study in Sweden showed that diabetics are about eight times more likely than non-diabetics to have a lower extremity amputation. The researchers evaluated only lower limb amputations performed due to clogged arteries in the leg in individuals 45 years of age or older. They compared the rate [...]

Juvenile Diabetes and The Coxsackie Virus

Recent research has emerged to reinforce the idea that viruses may cause juvenile (type 1) diabetes, which is an autoimmune disease. In autoimmune diseases, the body’s immune system mistakenly attacks the body’s own cells. In juvenile diabetes, immune cells attack the beta cells in the pancreas which are responsible for secreting insulin. One important role [...]

Risk Factors for Bone Infection in Diabetic Wounds Identified

Individuals with diabetes have a greater risk for developing open wounds (ulcers) due to reduced sensation and circulation. Diabetic ulcers can become infected and severe infection may reach the bone. The medical term for bone infection is osteomyelitis. Osteomyelitis associated with diabetic wounds worsens the chances of recovery. Treatment of bone infections involves prolonged antibiotic [...]

Orthoses Improve Walking after Stroke

British researchers analyzed 14 randomized controlled trials with 429 participants evaluating the effects of orthoses in people with stroke and other non-progressive brain lesions. They found that there was a significant and beneficial effect of lower limb orthoses on walking speed, walking step and stride length and weight distribution in standing. Social Bookmarking OptionsBlinklistBloglinesBlogmarksDiggdel.icio.usFacebookFurlMa.gnoliaNewsVineRedditStumbleUponTechnorati

Bone Marrow Cells May Help Reverse Diabetic Neuropathy

According to CDC data from 2005 about 60-70% of diabetics have some type of nerve damage and about 30% of diabetics over forty years of age have diabetic peripheral neuropathy. Diabetic neuropathy is an abnormality of the nervous system caused by diabetes. When referring to the human body and diabetic neuropathy, peripheral refers to the [...]

Stem Cell Injections May Prevent Amputations

The following is a press release by the American Podiatric Medical Association New Stem Cell Injections May Help Prevent Amputations: American Podiatric Medical Association Member Assisting in Breakthrough Clinical Trials October 20, 2008 Bethesda, MD– Poor blood flow to the lower limbs is a health condition that many Americans with diabetes experience. But without early [...]

Diabetic Foot Complications Reduced with Management

An abstract presented at the 2007 American Diabetes Association Scientific Session showed reduced lower extremity complications in diabetics who participated in a diabetic management program. Reduced Incidence of Diabetes Lower Extremity Complications During Participation in Diabetes Disease Management Programs Authors: CARTER COBERLEY, BRENT HAMAR, ZACKARY SAMPLES, MATTHEW MCGINNIS, SADIE COBERLEY, ANDRES PEREZ, DEXTER SHURNEY, Nashville, [...]